How Long Does it Take For Sertraline to Work For Premature Ejaculation?

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A 2019 study found that antidepressants known as selective serotonin reuptake inhibitors, such as sertraline (Zoloft), paroxetine (Paxil), citalopram (Celexa) or fluoxetine (Prozac), can improve premature ejaculation. These medications can be taken daily or on-demand.

If underlying psychological or relationship issues are contributing to your PE, talk with a therapist who is certified in treating PE. Your urologist can help refer you to one.

Dosage

Premature ejaculation (PE) is when semen exits the penis sooner than you want it to during sexual intercourse or other activities. Although PE is fairly common, it can have serious consequences for your quality of life and relationships. If you’re suffering from PE, your doctor may recommend medication.

Sertraline is an SSRI, or selective serotonin reuptake inhibitor, antidepressant drug that’s FDA-approved to treat depression and other mental health conditions. It increases the amount of serotonin in your brain by blocking its reabsorption into neurons. This causes a delayed reaction in parts of your brain that control ejaculation, delaying orgasms.

In one small study, 46 normally potent men with PE received daily doses of 25 mg, 50 mg, and 100 mg of sertraline for 6 weeks. At the lowest dose, orgasms were delayed from about 1 minute to 7.6 minutes. At the highest dose, orgasms were delayed from 1 to 16 minutes.

It’s also possible for people to take a low dose of sertraline on demand rather than daily, and this has also been shown to improve PE symptoms. However, it’s important to slowly lower your dose if you’re taking this medication on demand so that you don’t experience antidepressant discontinuation syndrome. This is a condition that can lead to flu-like symptoms, dizziness, and tremors. If you experience this side effect, seek emergency medical attention immediately.

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Symptoms

Premature ejaculation (PE) is when you ejaculate earlier than you should during sexual intercourse. PE can be caused by a number of factors, including anxiety, stress and relationship issues. It can also be caused by certain medical and biological conditions, such as erectile dysfunction or hyperthyroidism. SSRI antidepressants, such as sertraline, can help delay orgasms and reduce PE symptoms. Behavioral therapy techniques such as the squeeze stop-start method may also be helpful.

The FDA approves the use of SSRI antidepressants to treat a variety of mental health conditions, such as depression and panic disorders. Some studies have shown that SSRIs, like sertraline, can be used off-label to treat PE. They do so by raising serotonin levels in the brain, which helps to delay orgasms.

PE can be disruptive to a relationship, and it is important to talk to your partner about it. It can also be beneficial to seek out a psychologist, psychiatrist or couples therapist who can provide counseling to help you work through the issue.

Other treatment options include using a lubricant to slow down the rate of ejaculation and a behavior modification technique called the squeeze stop-start method. This involves stimulating the penis until you feel that you are close to ejaculating, then stopping and squeezing on the penis for a short period of time until the sensation passes. Medications such as tadalafil or sildenafil, which are used to treat erectile dysfunction, may also be effective in some cases.

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Side effects

Premature ejaculation is a common sexual condition that causes frustration for both the affected individual and their partner. It can lead to strained relationships, but the good news is that PE is treatable. There are several options available for treatment, including behavioral techniques and medications. One option that may be a good choice for some is sertraline. Sertraline is an antidepressant medication that works by raising serotonin levels in the brain. It is typically prescribed for mental health conditions, but it is also sometimes used off-label to treat PE. Research has found that taking the drug regularly can help delay ejaculation and improve bedroom duration.

It is important to discuss the use of sertraline with your health care provider. They will ask questions about your medical history and conduct a physical exam. Your provider may also order blood tests to check hormone levels.

Several studies have found that the medication can help to prevent PE in some people. It can be taken either on a daily basis or as needed. However, taking the drug daily appears to be more effective at treating PE. Using it as-needed can lead to fewer side effects, but it is important to monitor the symptoms closely. If you experience any serious side effects, talk to your doctor right away. Serious side effects can include suicidal thoughts, changes in mood, tremors, and rapid heart rate.

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Precautions

Premature ejaculation is one of the most common sexual dysfunctions experienced by men, with some studies suggesting up to 39 percent of men are affected. Fortunately, there are ways to overcome it. While there is no specific medication available to treat PE, several antidepressants can help. These include sertraline (Zoloft) and selective serotonin reuptake inhibitors (SSRIs). These are often used as PE treatments on an “off-label” basis, meaning that they have not been approved by the FDA for this purpose. However, SSRIs have been shown to improve sexual satisfaction and extend ejaculatory latency times.

The SSRIs in particular are prescribed to help with PE because they are known to increase serotonin levels, which helps with arousal and control over ejaculation. A small study that followed 46 normally potent men found that when SSRI pills were taken daily, they lasted longer in the bedroom. In fact, the average time it took for them to ejaculate was reduced from 1 minute to 7.6 minutes at the 25 mg dose and then to 13.1 and 16.4 minutes at the 50 and 100 mg doses respectively.

If you’re interested in trying SSRIs to treat PE, a GP will need to consider your symptoms and medical history to determine whether this is appropriate. If you’re worried about the side effects of SSRIs, there are anesthetic creams that can be applied to your penis to make it less sensitive. However, these creams are only suitable for occasional use and may have other unwanted side effects, such as a loss of sensation during sex.

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